GHK-Cu

GHK-Cu is a naturally occurring tripeptide, glycyl-L-histidyl-L-lysine, bound to a copper(II) ion. It was first isolated from human plasma and is also present in saliva and urine, with levels that decline with age. Widely referenced in skin- and matrix-biology research, it is supplied by NOX as a lyophilised research reference material for research use only; the information here is educational, not medical or cosmetic guidance.

The tripeptide has a high affinity for copper(II) and spontaneously forms a stable GHK–copper complex, so in research it is characterised as both a signalling peptide and a carrier that shuttles copper. Much of the published interest concerns how this copper co-ordination shapes its behaviour in laboratory models. This is educational context; GHK-Cu is a research reference material supplied for research use only.

GHK-Cu is most often examined in connective-tissue, extracellular-matrix and skin-biology models, where a recurring theme is "balanced remodelling", it is reported to modulate matrix metalloproteinases (MMPs) alongside their TIMP inhibitors while stimulating collagen, elastin and proteoglycans such as decorin. The focus is mechanism rather than applied use. GHK-Cu is supplied for research use only and carries no medical or cosmetic claim.

Lyophilised GHK-Cu is supplied as a sealed, freeze-dried powder and is generally kept frozen and away from light, typically stored at around -20°C for long-term stability, while for shorter periods it can be kept in the fridge at 2–8°C. Keeping the vial sealed limits moisture uptake and helps preserve the dry material. This describes general laboratory handling of lyophilised research compounds and is provided for research use only, not as guidance for any other use.

GHK-Cu is supplied as a sealed, lyophilised (freeze-dried) powder in a glass vial. Freeze-drying removes water so the material stays stable during storage and transport until a researcher reconstitutes it for laboratory work. It is provided as a research reference material for research use only, with no human, clinical or veterinary application.

Bacteriostatic water is commonly used to reconstitute lyophilised research compounds because the small amount of benzyl alcohol it contains helps limit microbial growth in a multi-use vial. It simply dissolves the freeze-dried powder into a liquid so the material can be handled in the laboratory. Reconstitution is performed strictly within a research context; GHK-Cu is supplied by NOX for research use only.

Once reconstituted, GHK-Cu is in solution and generally less stable than the dry powder, so the liquid is typically kept in the fridge at 2–8°C and protected from light. Researchers usually prepare only what a study requires and record the reconstitution date. This reflects general laboratory handling of reconstituted research materials and is offered for research-use-only context, not as guidance for human or veterinary use.

GHK-Cu is supplied as a lyophilised powder in 50 mg and 100 mg. The stated strength is the mass of compound sealed in the vial before reconstitution; the working concentration depends on the volume of solvent a researcher adds during preparation. All presentations are research reference materials supplied for research use only.

Yes. GHK-Cu is supplied by NOX strictly as a research reference material for laboratory and analytical use. It is not a medicinal product, food, cosmetic or veterinary product, and nothing in these answers should be read as guidance for human or animal use. All information here is provided for educational and research context only.